Vast tissue and organ damage are not infrequent. When bone or muscle tissues are critically injured and cannot heal by themselves, the only solution remaining requires, sometimes, harvesting tissues from another part in the patient body and implanting it back. Such self or autologous transplantations often lead to grave morbidities, infections, and complications. In other cases, when tissues and organs are not redundant, organ donation remains the only option with considerable limitations of donor shortage and immune rejection.

Tissue engineering seeks to overcome the limitations of self-transplants and organ donations by growing functional tissues outside the human body. In Bonus Biogroup, we developed and perfected means to sample cells from the patient using a minimally invasive process, professionalize these cells, and use them in conjugation with natural tissue scaffolds and specialized automated bioreactor systems to create personalized, viable, and functional human tissues.