Tissue engineering

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Path 41Designed to harness the power of nature, tissue engineering technologies invented by Bonus BioGroup combine cells and scaffolds capable of building, nourishing, and integrating lab-grown tissues, personalized using the patient's cells for optimal regeneration of hard and soft tissues
Path 42

Tissue engineering

bonus 1a

Path 41Designed to harness the power of nature, tissue engineering technologies invented by Bonus BioGroup combine cells and scaffolds capable of building, nourishing, and integrating lab-grown tissues, personalized using the patient's cells for optimal regeneration of hard and soft tissues
Path 42

Organs and tissues injured or damaged by trauma or disease are hard to replace.

Vast tissue and organ damage are not infrequent. When bone or muscle tissues are critically injured and cannot heal by themselves, the only solution remaining requires, sometimes, harvesting tissues from another part in the patient body and implanting it back. Such self or autologous transplantations often lead to grave morbidities, infections, and complications. In other cases, when tissues and organs are not redundant, organ donation remains the only option with considerable limitations of donor shortage and immune rejection.

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Organs and tissues injured or damaged by trauma or disease are hard to replace.

Vast tissue and organ damage are not infrequent. When bone or muscle tissues are critically injured and cannot heal by themselves, the only solution remaining requires, sometimes, harvesting tissues from another part in the patient body and implanting it back. Such self or autologous transplantations often lead to grave morbidities, infections, and complications. In other cases, when tissues and organs are not redundant, organ donation remains the only option with considerable limitations of donor shortage and immune rejection.

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It takes a village to grow a tissue

Tissue engineering seeks to overcome the limitations of self-transplants and organ donations by growing functional tissues outside the human body.

In Bonus Biogroup, we developed and perfected means to sample cells from the patient using a minimally invasive process, professionalize these cells, and use them in conjugation with natural tissue scaffolds and specialized automated bioreactor systems to create personalized, viable, and functional human tissues.

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BonoFill, the world's first tissue-engineered viable bone graft for treating severe bone defects, is our leading tissue engineering product in clinical development.

Combining cells with different functions and a natural scaffold, BonoFill™ is applicable for all indications and bone gap sizes. Using BonoFill, bones were successfully regenerated in dozens of patients already who recovered from years of disabilities.

BonoFill, the world's first tissue-engineered viable bone graft for treating severe bone defects, is our leading tissue engineering product in clinical development.

Combining cells with different functions and a natural scaffold, BonoFill™ is applicable for all indications and bone gap sizes. Using BonoFill, bones were successfully regenerated in dozens of patients already who recovered from years of disabilities.

Artificial blood vessels for integrating transplanted lab-grown organs

Engineered tissues that do not contain blood vessels may suffer from a limited supply of nutrients and oxygen to the cells and impaired waste removal, often leading to transplant rejection and necrosis, demanding removal.

The technology for producing an artificial blood vessel network developed by Bonus Biogroup presents the possibility of integrating blood vessels into engineered tissues and organs as an essential part of their manufacturing, which may improve their transplantation success.

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INFORMATION FOR INVESTORS

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